Ducharme N G, Hackett R P, Fubini S L, Erb H N
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
Vet Surg. 1991 May-Jun;20(3):180-4. doi: 10.1111/j.1532-950x.1991.tb00332.x.
Twenty Thoroughbred and Standardbred horses underwent endoscopic evaluation of arytenoid cartilage movement twice within 1 week. Each time, a flexible endoscope was passed without sedation through the right nostril and the left nostril, and through the right nostril 5 minutes after administration of xylazine hydrochloride (0.55 mg/kg or 1.1 mg/kg intravenously). Laryngeal cartilage movement was videorecorded. All videotaped images were reviewed by three veterinarians and subjectively placed in one of four grades. The intraobserver agreement rate varied from 52.6% for examination under sedation with 1.1 mg/kg of xylazine to 89.5% for unsedated reexamination through the left nostril. The effect of the various observations on median laryngeal grade was calculated. Examination under xylazine hydrochloride at either dosage yielded a change in median laryngeal grade from the unsedated examination in 45% of the evaluations. Reevaluation through the right or left nostril resulted in a different median laryngeal grade in 21% and 5% of the examinations, respectively. Objective measurements of the rima glottidis obtained by computer-assisted morphometric analysis of the recorded laryngeal images allowed laryngeal images to be dichotomized regardless of the condition of endoscopic examination. Endoscopic evaluation of laryngeal cartilage movement is subjective and is influenced by sedation with xylazine, evaluation through the alternate nostril, and different day of examination. The most consistent evaluation was obtained during repeated examination through the left nostril.
20匹纯种马和标准赛马在1周内接受了两次杓状软骨运动的内镜评估。每次，在未使用镇静剂的情况下，通过右鼻孔和左鼻孔插入一根柔性内窥镜，并在静脉注射盐酸赛拉嗪（0.55mg/kg或1.1mg/kg）5分钟后通过右鼻孔插入。对喉软骨运动进行录像。所有录像图像由三名兽医进行评估，并主观地分为四个等级之一。观察者内一致性率从使用1.1mg/kg赛拉嗪镇静下检查的52.6%到通过左鼻孔未镇静复查的89.5%不等。计算了各种观察对喉中位等级的影响。在45%的评估中，使用任一剂量盐酸赛拉嗪进行检查时，喉中位等级与未镇静检查相比有所变化。分别在21%和5%的检查中，通过右鼻孔或左鼻孔重新评估得到了不同的喉中位等级。通过对记录的喉部图像进行计算机辅助形态计量分析获得的声门裂客观测量结果，使得无论内镜检查情况如何，喉部图像都可以分为两类。喉软骨运动的内镜评估是主观的，受赛拉嗪镇静、通过交替鼻孔评估以及不同检查日期的影响。通过左鼻孔重复检查时获得的评估最为一致。
