Wenzel M, Wenzel G, Klauke M, Kerl J, Hund-Rinke K
Krankenhaus Kloster Grafschaft, Zentrum für Pneumologie, Beatmungs- und Schlafmedizin, Schmallenberg.
Pneumologie. 2008 Jun;62(6):324-9. doi: 10.1055/s-2008-1038127.
Patients receiving mechanical ventilation and oxygen therapy frequently complain about the dryness of their airways. Humidifiers increase air humidity by generating water vapour and thus preventing the mucosa from desiccation. In this bench study, we compared the efficiency of several humidifiers.
Two identical humidifiers of each type (HC 602, HumiCare 200, Humid Aire 2i, minni-Max, MR 730 AGM, REMstar, Sirius, Somnia2, Somno Comfort2, VENTIclick, VIVO 30) were measured at three different heating intensities (low, medium, high) and three different flow rates (20, 55 and 90 l/min). The relative humidity at the exit of the tube and the temperature of the water in the heating chamber were registered. Additionally, we measured the humidity of the oxygen humidifier Respiflo at 1 - 5 l/min, the Respiflo was filled with either NaCl 0.9% or Aqua dest. Measurements were taken in a climatic chamber at 20 degrees C and 50% relative humidity. The atmospheric pressure was taken into consideration.
The MR 730 AGM and Humicare 200 generated a constant relative humidity of 100%. Among the remaining humidifiers, only the HC 602, HumidAire 2i and REMstar reached a humidity of about 95% at high flow rates. The Minni-Max, Somnia2 and VIVO 30 generated a humidity of 95% still at a flow rate of 55 l/min. The Sirius, Somno Comfort2 and the VENTIclick generated this amount of humidity only at low flow rates of 20 l/min. The three humidifiers mentioned last generated a relative humidity of only 68 - 76 at high flow rates of 90 l/min. The Respiflo generates a humidity of about 90% at each flow rate (1 - 5 l/min.), independent of being filled with NaCl 0.9% or Aqua dest.
Factors determinating the efficacy of humidifiers are the velocity of the airstream, the temperature of the water, the contact surface of the air and water compartments and the turbulence of the airstream. In vivo the amount of leakage is a very important determinant for the velocity of the airstream. In the care of mechanically ventilated patients one should have an approximate idea of the magnitude of the applied air flows. The limitations of some humidifiers should be known. The simple presence of a humidifier in combination with a respirator does not mean that the problem of dryness of the airway mucosa is eliminated.
接受机械通气和氧疗的患者经常抱怨气道干燥。加湿器通过产生水蒸气来增加空气湿度,从而防止黏膜干燥。在这项实验研究中,我们比较了几种加湿器的效率。
每种类型的两个相同加湿器(HC 602、HumiCare 200、Humid Aire 2i、minni-Max、MR 730 AGM、REMstar、Sirius、Somnia2、Somno Comfort2、VENTIclick、VIVO 30)在三种不同加热强度(低、中、高)和三种不同流速(20、55和90升/分钟)下进行测量。记录管出口处的相对湿度和加热室内水的温度。此外,我们在1 - 5升/分钟的流速下测量了氧气加湿器Respiflo的湿度,Respiflo中填充的是0.9%氯化钠溶液或蒸馏水。测量在温度为20摄氏度、相对湿度为50%的气候箱中进行。考虑了大气压力。
MR 730 AGM和HumiCare 200产生的相对湿度恒定为100%。在其余加湿器中,只有HC 602、HumidAire 2i和REMstar在高流速下达到约95%的湿度。Minni-Max、Somnia2和VIVO 30在流速为55升/分钟时仍能产生95%的湿度。Sirius、Somno Comfort2和VENTIclick仅在20升/分钟的低流速下能产生此湿度。最后提到的三种加湿器在90升/分钟的高流速下产生的相对湿度仅为68 - 76。Respiflo在每个流速(1 - 5升/分钟)下产生的湿度约为90%,与填充的是0.9%氯化钠溶液还是蒸馏水无关。
决定加湿器效率的因素有气流速度、水的温度、空气和水腔室的接触面积以及气流的湍流程度。在体内,泄漏量是气流速度的一个非常重要的决定因素。在护理机械通气患者时,应该对所应用气流的大小有一个大致的概念。应该了解一些加湿器的局限性。仅仅在呼吸器上配备加湿器并不意味着气道黏膜干燥的问题就得到了解决。