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酷似牙源性角化囊肿的下颌骨骨内施万瘤,伴术后病理性骨折。

Intraosseous mandibular schwannoma mimicking an odontogenic keratocyst, with a postsurgical pathological fracture.

作者信息

Gallego L, Junquera L, Rodríguez-Recio C, Fresno M F

机构信息

Department of Oral and Maxillofacial Surgery, Central University Hospital of Oviedo, Oviedo, Spain.

出版信息

J Laryngol Otol. 2009 May;123(5):560-2. doi: 10.1017/S0022215108002934. Epub 2008 Jun 9.

Abstract

OBJECTIVE

Schwannomas are slowly growing tumours derived from Schwann cells. We present a clinical case of schwannoma in the mandibular angle.

METHOD

Case report and a review of the world literature concerning intraosseous schwannoma of the maxillofacial region.

RESULTS

Schwannomas or neurilemmomas are slow-growing, benign neoplasms derived from Schwann cells. Intraoral lesions are unusual and intraosseous schwannomas are even rarer, representing less than 1 per cent of benign primary tumours of the bones. We present a clinical case of schwannoma in the mandibular angle mimicking a keratocystic odontogenic tumour, with a complicated posterior evolution.

CONCLUSION

Clinically, neurilemmomas are slow-growing tumours which may be present for years before becoming symptomatic. Radiographically, the image may be suggestive of a benign process such as an odontogenic keratocyst. Histological analysis of the specimens obtained is extremely important in order to establish the final diagnosis.

摘要

目的

施万细胞瘤是起源于施万细胞的缓慢生长的肿瘤。我们报告一例下颌角施万细胞瘤的临床病例。

方法

病例报告并回顾世界范围内有关颌面部骨内施万细胞瘤的文献。

结果

施万细胞瘤或神经鞘瘤是起源于施万细胞的生长缓慢的良性肿瘤。口腔内病变不常见,骨内施万细胞瘤更为罕见,占原发性骨良性肿瘤的比例不到1%。我们报告一例下颌角施万细胞瘤的临床病例,该病例酷似牙源性角化囊性瘤,后期病情复杂。

结论

临床上,神经鞘瘤生长缓慢,可能在出现症状前已存在数年。影像学上,其表现可能提示为良性病变,如牙源性角化囊肿。为明确最终诊断,对所取标本进行组织学分析极为重要。

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