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欧洲心脏手术风险评估系统(EuroSCORE)和一个本地模型均能持续预测冠状动脉手术死亡率,且呈现出互补特性。

The EuroSCORE and a local model consistently predicted coronary surgery mortality and showed complementary properties.

作者信息

Ribera Aida, Ferreira-Gonzalez Ignacio, Cascant Purificació, Pons Joan M V, Permanyer-Miralda Gaietà

机构信息

CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.

出版信息

J Clin Epidemiol. 2008 Jul;61(7):663-70. doi: 10.1016/j.jclinepi.2006.10.025.

Abstract

OBJECTIVE

To revalidate a local model for prediction of in-hospital mortality after coronary surgery several years after its introduction and the EuroSCORE in a specific area within its original scope. To assess the specific advantages of one type of instrument over the other in a definite context.

STUDY DESIGN AND SETTING

Data from consecutive patients undergoing a first isolated coronary artery bypass between November 2001 and November 2003 in five hospitals in Catalonia were prospectively collected.

RESULTS

The study included 1,605 patients. Areas under the receiver-operating characteristics curves were around 0.75 for both models. Calibration was low for both models and the local model significantly overestimated risk. The ordering of operating centers by performance was identical with each strategy but the centers labeled as outliers differed.

CONCLUSION

(1) Evaluation of performance of individual hospitals was consistent using both systems and almost identical when they were internally recalibrated, (2) The impact of the benchmark population characteristics on model performance may be greater than that of risk factors considered for score calculation, (3) Promoting the use of a widely used instrument as the EuroSCORE might be sufficient for most evaluations. Local scales can be useful to highlight locally relevant features and temporal trends.

摘要

目的

在引入本地模型预测冠状动脉手术后院内死亡率数年之后,以及在其原始范围内的特定区域重新验证欧洲心脏手术风险评估系统(EuroSCORE)。在特定背景下评估一种工具相对于另一种工具的具体优势。

研究设计与设置

前瞻性收集了2001年11月至2003年11月在加泰罗尼亚五家医院接受首次单纯冠状动脉搭桥手术的连续患者的数据。

结果

该研究纳入了1605例患者。两种模型的受试者工作特征曲线下面积均约为0.75。两种模型的校准度都较低,且本地模型显著高估了风险。按性能对手术中心进行排序时,两种策略的结果相同,但被标记为异常值的中心不同。

结论

(1)使用两种系统对各医院性能的评估是一致的,并且在内部重新校准后几乎相同;(2)基准人群特征对模型性能的影响可能大于评分计算中所考虑的风险因素的影响;(3)推广使用像欧洲心脏手术风险评估系统这样广泛使用的工具可能足以满足大多数评估。本地量表有助于突出本地相关特征和时间趋势。

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