Schneider Barbara, Schnabel Axel, Wetterling Tilman, Bartusch Bernadette, Weber Bernhard, Georgi Klaus
Center of Psychiatry, Department of Psychiatry and Psychotherapy, Johann Wolfgang Goethe-University Frankfurt/Main, Frankfurt/Main, Germany.
J Pers Disord. 2008 Jun;22(3):233-45. doi: 10.1521/pedi.2008.22.3.233.
There is a lack of psychological autopsy studies assessing the influence of axis II disorders on other risk factors for suicide. Therefore, we investigated if the estimated suicide risk for axis I disorders and socio-demographic factors was modified by personality disorders. Psychiatric disorders were evaluated by a semi-structured interview including the Structured Clinical Interview for DSM-IV Axis I (SCID-I) and Personality Disorders (SCID-II) by psychological autopsy method in 163 completed suicides and by personal interview in 396 population-based control persons. Personality disorders modify suicide risk, differently for affective disorders, substance use disorders, smoking, life events during the last three months, and socio-demographic factors such as being single. Estimated suicide risk for socio-demographic factors and life events is not substantially altered following adjustment for affective disorders or substance use disorders. These findings suggest that treatment of personality disorders is essential for suicide prevention.
目前缺乏评估轴II障碍对其他自杀风险因素影响的心理解剖学研究。因此，我们调查了人格障碍是否会改变轴I障碍和社会人口学因素的估计自杀风险。采用心理解剖学方法，通过半结构化访谈（包括针对DSM-IV轴I障碍的结构化临床访谈（SCID-I）和人格障碍访谈（SCID-II））对163例自杀死亡者进行了精神障碍评估，并通过个人访谈对396名基于人群的对照者进行了评估。人格障碍会改变自杀风险，对情感障碍、物质使用障碍、吸烟、过去三个月内的生活事件以及诸如单身等社会人口学因素的影响各不相同。在对情感障碍或物质使用障碍进行调整后，社会人口学因素和生活事件的估计自杀风险没有实质性改变。这些发现表明，治疗人格障碍对预防自杀至关重要。
