Waddell L, Taylor M
Southern General Hospital, Glasgow, UK.
J Psychopharmacol. 2008 May;22(3):238-43. doi: 10.1177/0269881107087976.
We aimed to construct and assess a new self rating scale to detect the side effects of second generation antipsychotics. This scale was designed to allow a timely, sensitive and reliable method of gathering information on the number and severity of side effects an individual suffers from. The Glasgow Antipscyhotic Side-effect Scale (GASS) was developed after literature review, discussion with members of the mental health team and with service user feedback. Fifty indivudals taking second generation antipsychotics completed the GASS along with the Liverpool Univeristy Neuroleptic Side Effect Rating Scale, and one week later completed the GASS for a second time. Fifty comparison subjects also completed the GASS. The GASS was shown to have good discrimatory power and construct validity, along with good re-test reliablity, and is put forward as a short, helpful and valid clinical tool.
我们旨在构建并评估一种新的自评量表,以检测第二代抗精神病药物的副作用。该量表旨在提供一种及时、敏感且可靠的方法,用于收集个体所遭受副作用的数量和严重程度的信息。格拉斯哥抗精神病药物副作用量表(GASS)是在文献综述、与精神卫生团队成员讨论以及服务使用者反馈的基础上开发的。50名服用第二代抗精神病药物的个体完成了GASS以及利物浦大学抗精神病药物副作用评定量表,一周后再次完成GASS。50名对照受试者也完成了GASS。结果表明,GASS具有良好的区分能力和结构效度,同时具有良好的重测信度,被提出作为一种简短、有用且有效的临床工具。