Hedges Thomas R, Vuong Laurel N, Gonzalez-Garcia Alberto O, Mendoza-Santiesteban Carlos E, Amaro-Quierza Maria Luz
New England Eye Center, Tufts University School of Medicine, Boston, Massachusetts, USA.
Arch Ophthalmol. 2008 Jun;126(6):812-5. doi: 10.1001/archopht.126.6.812.
To demonstrate the development of subfoveal fluid associated with optic disc swelling from nonarteritic anterior ischemic optic neuropathy.
Optical coherence tomographic studies obtained during a 3-year period (October 1, 2003, to December 30, 2006) from 76 patients who developed ischemic optic neuropathy from 2 institutions were evaluated. The presence or absence, and the distribution, of subretinal fluid was determined.
Seventy-six patients underwent macular optical coherence tomography within 4 weeks of developing sudden loss of vision in one eye, decreased visual acuity, a visual field defect, a relative afferent pupillary defect, and optic disc swelling with peripapillary hemorrhages. Eight patients had apparent subretinal fluid extending into the subfoveal space. Visual acuity improved in 5 of the 8 patients as the subfoveal fluid resolved.
Subretinal fluid develops in some patients with nonarteritic anterior ischemic optic neuropathy and may contribute to some of the visual loss associated with this condition. Furthermore, resolution of the subretinal fluid could account for some of the visual improvement that can follow anterior ischemic optic neuropathy.
证明非动脉炎性前部缺血性视神经病变所致视盘肿胀相关的黄斑下液的形成。
对来自2家机构的76例发生缺血性视神经病变的患者在3年期间（2003年10月1日至2006年12月30日）所获得的光学相干断层扫描研究进行评估。确定视网膜下液的有无及其分布情况。
76例患者在单眼突然视力丧失、视力下降、视野缺损、相对性传入瞳孔障碍以及视盘肿胀伴视乳头周围出血后的4周内接受了黄斑光学相干断层扫描。8例患者有明显的视网膜下液延伸至黄斑下间隙。随着黄斑下液的消退，8例患者中有5例视力得到改善。
非动脉炎性前部缺血性视神经病变的一些患者会出现视网膜下液，这可能是导致该疾病相关部分视力丧失的原因。此外，视网膜下液的消退可能是前部缺血性视神经病变后部分视力改善的原因。
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