Orzechowski K, Rudowski M, Rzaca M
Faculty of Chemistry, Wrocław University, Poland.
Physiol Meas. 2008 Jun;29(6):S321-30. doi: 10.1088/0967-3334/29/6/S27. Epub 2008 Jun 11.
Dielectric properties of breast tissue obtained from 131 patients were investigated by an open-ended probe separated from the tissue by a dielectric film (plastic foil). The film decreases the measured capacitance, but the content of blood and body liquids has little effect on the measured quantity. We found that in cancerous tissue the electric capacity (related to the permittivity) measured at f > or = 10 MHz using the modified probe is higher than that in normal tissue. The dielectric assignment was confirmed by histopathology in 94% of investigated cases. High efficiency in differentiation between normal and cancer breast tissues and the feasibility of fulfilling of aseptic conditions (a film covering the probe) are promising in intra-operative cancer diagnostics.
通过一个由介电膜(塑料薄膜)与组织隔开的开口探头,对131名患者的乳腺组织的介电特性进行了研究。该薄膜会降低测量的电容,但血液和体液的含量对测量值影响很小。我们发现,使用改良探头在f≥10 MHz时测量的癌组织电容(与介电常数相关)高于正常组织。在94%的研究病例中,组织病理学证实了介电诊断结果。在术中癌症诊断中,正常乳腺组织与癌组织之间的高效区分以及实现无菌条件(探头覆盖薄膜)的可行性很有前景。