Kato Noritada, Takahashi Masaya, Aratake Yutaka, Watanabe Mayumi, Sakata Yumi, Kojima Reiko, Kakinuma Mitsuru, Shibaoka Michi, Tanaka Katsutoshi
Department of Occupational Mental Health, Graduate School of Medical Science Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan.
Ind Health. 2008 Jul;46(3):233-8. doi: 10.2486/indhealth.46.233.
Sleep-disordered breathing (SDB) is the major determinants of hypertension. Recent studies indicated sleep duration, in addition to shift work, were also associated with hypertension. But very little attention has been paid to these two factors when looking at the effects of SDB on blood pressure. We conducted the present study to evaluate the relationship between SDB and hypertension adjusting for sleep duration and shift work in a sample of Japanese steel workers. In this cross-sectional study, we measured blood pressure and oxygen desaturations index (ODI) by nocturnal pulse oximetry of 249 male workers aged 20 to 65 yr. SDB was defined by 3%ODI level of 15 or more events per hour. Logistic regression analyses were performed to estimate the associations of SDB with hypertension after adjustment for age, body mass index, alcohol intake, smoking, usual sleep duration, shift work, and occupation. The prevalence of SDB was 18.1%. The adjusted odds ratio of hypertension for high (> or =15) vs. low (<15) category of 3%ODI level was 2.86 (95% confidence interval, 1.23-6.66). The significant association between SDB and hypertension suggests that screening for SDB among steel workers is useful for prevention of hypertension.
睡眠呼吸障碍（SDB）是高血压的主要决定因素。最近的研究表明，除了轮班工作外，睡眠时间也与高血压有关。但是，在研究SDB对血压的影响时，这两个因素很少受到关注。我们进行了本研究，以评估在一组日本钢铁工人样本中，调整睡眠时间和轮班工作后SDB与高血压之间的关系。在这项横断面研究中，我们通过夜间脉搏血氧饱和度测定法测量了249名年龄在20至65岁之间的男性工人的血压和氧饱和度下降指数（ODI）。SDB定义为每小时3%ODI水平有15次或更多事件。进行逻辑回归分析，以估计在调整年龄、体重指数、酒精摄入量、吸烟、通常睡眠时间、轮班工作和职业后SDB与高血压之间的关联。SDB的患病率为18.1%。3%ODI水平高（≥15）与低（<15）类别相比，高血压的调整后比值比为2.86（95%置信区间，1.23 - 6.66）。SDB与高血压之间的显著关联表明，在钢铁工人中筛查SDB对预防高血压是有用的。
