Schostak M, Miller K, Schrader M
Department of Urology, Charité Universitätsmedizin Berlin, Berlin , Germany.
Front Radiat Ther Oncol. 2008;41:7-14. doi: 10.1159/000139873.
Radical prostatectomy for treatment of prostate cancer is a technically sophisticated operation. Simpler therapies have therefore been developed in the course of decades. The decisive advantage of a radical operation is the chance of a cure with minimal collateral damage. It is the only approach that enables precise tumor staging. The 10-year progression-free survival probability is approximately 85% for a localized tumor with negative resection margins. This high cure rate is unsurpassed by competitive treatment modalities. Nowadays, experienced surgeons achieve excellent functional results (for example, recovery of continence and erectile function) with minimum morbidity. Even in the locally advanced stage, results are very good compared to those obtained with other treatment modalities. Pathological staging enables stratified adjuvant therapy based on concrete information. The overall prognosis can thus be significantly improved.
根治性前列腺切除术治疗前列腺癌是一项技术复杂的手术。因此，在几十年间已开发出更简单的治疗方法。根治性手术的决定性优势在于有机会以最小的附带损害实现治愈。它是唯一能够进行精确肿瘤分期的方法。对于切缘阴性的局限性肿瘤，10年无进展生存率约为85%。这种高治愈率是其他竞争性治疗方式无法比拟的。如今，经验丰富的外科医生能以最低的发病率取得出色的功能结果（例如，恢复控尿和勃起功能）。即使在局部晚期，与其他治疗方式相比，效果也非常好。病理分期能够基于具体信息进行分层辅助治疗。从而可显著改善总体预后。
