Park Seo Yong, Kim Jung Jun, Kim Tae Heon, Lim Soo Hyun, Han Deok Hyun, Park Byung Kwan, Kim Chan Kyo, Kwon Ghee Young, Choi Han Yong, Lee Hyun Moo
Department of Urology, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean J Urol. 2010 May;51(5):308-12. doi: 10.4111/kju.2010.51.5.308. Epub 2010 May 19.
We aimed to assess the clinical value of endorectal magnetic resonance imaging (MRI) in predicting extraprostatic extension and seminal vesicle invasion in patients with clinically localized prostate cancer.
A total of 54 patients who underwent radical prostatectomy for clinically localized prostate cancer were retrospectively analyzed. The findings of endorectal MRI, performed at least 3 weeks after biopsy, were compared with the pathological results of radical prostatectomy specimens. The sensitivity, specificity, and accuracy of the detection of extraprostatic extension and seminal vesicle invasion were calculated.
The sensitivity, specificity, and accuracy of the endorectal MRI findings were 50.0%, 82.6%, and 77.8% for the detection of extraprostatic extension, respectively, and 75.0%, 92.0%, and 90.7% for the detection of seminal vesicle invasion, respectively. The sensitivity of endorectal MRI in the detection of extraprostatic extension improved as the Gleason score increased.
Endorectal MRI findings demonstrated modest sensitivity for predicting extraprostatic extension, whereas specificity was relatively high. In addition, endorectal MRI showed better sensitivity for detecting high-grade tumors.
我们旨在评估直肠内磁共振成像（MRI）在预测临床局限性前列腺癌患者前列腺外扩展和精囊侵犯方面的临床价值。
对54例因临床局限性前列腺癌接受根治性前列腺切除术的患者进行回顾性分析。将活检后至少3周进行的直肠内MRI检查结果与根治性前列腺切除标本的病理结果进行比较。计算前列腺外扩展和精囊侵犯检测的敏感性、特异性和准确性。
直肠内MRI检查结果对前列腺外扩展检测的敏感性、特异性和准确性分别为50.0%、82.6%和77.8%，对精囊侵犯检测的敏感性、特异性和准确性分别为75.0%、92.0%和90.7%。直肠内MRI检测前列腺外扩展的敏感性随Gleason评分增加而提高。
直肠内MRI检查结果在预测前列腺外扩展方面显示出中等敏感性，而特异性相对较高。此外，直肠内MRI在检测高级别肿瘤方面显示出更好的敏感性。
