Reedijk Wouter B, van Rijn Monique A, Roelofs Karin, Tuijl Jolien P, Marinus Johan, van Hilten Jacobus J
Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Mov Disord. 2008 Aug 15;23(11):1551-9. doi: 10.1002/mds.22159.
The objective of this study was to evaluate psychological features in severely affected patients with complex regional pain syndrome type I- (CRPS-I) related dystonia. Personality traits, psychopathology, dissociative experiences, the number of traumatic experiences, and quality of life were studied in 46 patients. Findings were compared with two historical psychiatric control groups [54 patients with conversion disorder (CD) and 50 patients with affective disorders (AD)] and normative population data. The CRPS-I patients showed elevated scores on the measures for somatoform dissociation, traumatic experiences, general psychopathology, and lower scores on quality of life compared with general population data, but had significantly lower total scores on the measures for personality traits, recent life events, and general psychopathology compared with the CD and AD patients. Rates of early traumatic experiences were comparable with the CD and AD patients, and the level of somatoform dissociation was comparable to the CD patients, but was elevated in comparison to the AD patients. Early traumatic experiences were reported in 87% of the CRPS-I patients and were found to be moderately related to somatoform dissociative experiences, indicating that early traumatic experiences might be a predisposing, although not a necessary factor for the development of CRPS-I-related dystonia. Although the psychological profile of the patients with CRPS-I-related dystonia shows some elevations, there does not seem to be a unique disturbed psychological profile on a group level.
本研究的目的是评估重度受累的Ⅰ型复杂性区域疼痛综合征（CRPS -Ⅰ）相关肌张力障碍患者的心理特征。对46例患者的人格特质、精神病理学、分离体验、创伤经历数量及生活质量进行了研究。将研究结果与两个历史精神病学对照组[54例转换障碍（CD）患者和50例情感障碍（AD）患者]以及正常人群数据进行了比较。与正常人群数据相比，CRPS -Ⅰ患者在躯体形式分离、创伤经历、一般精神病理学测量方面得分升高，在生活质量方面得分较低，但与CD和AD患者相比，在人格特质、近期生活事件和一般精神病理学测量方面的总分显著较低。早期创伤经历的发生率与CD和AD患者相当，躯体形式分离水平与CD患者相当，但与AD患者相比有所升高。87%的CRPS -Ⅰ患者报告有早期创伤经历，且发现其与躯体形式分离体验中度相关，这表明早期创伤经历可能是CRPS -Ⅰ相关肌张力障碍发生的一个易感因素，尽管不是必要因素。尽管CRPS -Ⅰ相关肌张力障碍患者的心理特征有一些升高，但在群体水平上似乎没有独特的心理紊乱特征。
