Araujo A B, Travison T G, Esche G R, Holick M F, Chen T C, McKinlay J B
New England Research Institutes, Watertown, MA 02472, USA.
Osteoporos Int. 2009 Feb;20(2):245-55. doi: 10.1007/s00198-008-0652-9. Epub 2008 Jun 12.
There are few data on the skeletal health of Hispanic men. We observed differences in vitamin D deficiency and low BMD between Hispanic ethnic subgroups that persisted with adjustment for risk factors. Our data indicate a substantial burden of low BMD and vitamin D deficiency among Hispanic men.
Disparities within ethnic groups are generally ignored, but in evolving populations they may have implications for public health. We examined ethnic variation in serum 25-hydroxyvitamin D [25(OH)D] and bone mineral density (BMD) among Hispanic American men.
Three hundred and fifty-eight Hispanic males 30 to 79 years of age were studied. Logistic regression models assessed variation in odds of vitamin D deficiency (<20 ng/mL) and low BMD (T-score<-1) by ethnicity, with and without adjustment for risk factors (age, smoking, occupation, physical activity, body mass index, and sunlight exposure).
Vitamin D deficiency was most common among Puerto Rican (26%), compared with Dominican (21%), Central American (11%), and South American (9%) men. Percentages with low BMD were: South American (44%), Puerto Rican (34%), Dominican (29%), and Central American (23%). Adjustment for age and risk factors failed to account for Hispanic subgroup differences in vitamin D deficiency and low BMD. Population estimates indicate a substantial burden of low BMD and vitamin D deficiency among Hispanic men.
Our findings underscore the importance of examining the skeletal health of Hispanic subgroups, and suggest that a considerable number of Hispanic men may be at elevated risk of fracture and vitamin D deficiency.
关于西班牙裔男性骨骼健康的数据很少。我们观察到西班牙裔不同亚组之间维生素D缺乏和低骨密度存在差异，在对风险因素进行调整后，这些差异仍然存在。我们的数据表明西班牙裔男性中低骨密度和维生素D缺乏的负担相当大。
种族群体内部的差异通常被忽视，但在不断变化的人群中，它们可能对公共卫生有影响。我们研究了美国西班牙裔男性血清25-羟基维生素D[25(OH)D]和骨矿物质密度(BMD)的种族差异。
研究了358名年龄在30至79岁之间的西班牙裔男性。逻辑回归模型评估了按种族划分的维生素D缺乏(<20 ng/mL)和低骨密度(T评分<-1)的几率差异，同时对风险因素(年龄、吸烟、职业、身体活动、体重指数和阳光照射)进行了调整和未调整的情况。
波多黎各男性中维生素D缺乏最为常见(26%)，相比之下，多米尼加男性为(21%)，中美洲男性为(11%)，南美洲男性为(9%)。低骨密度的百分比分别为：南美洲(44%)、波多黎各(34%)、多米尼加(29%)和中美洲(23%)。对年龄和风险因素进行调整后，仍无法解释西班牙裔亚组在维生素D缺乏和低骨密度方面的差异。人群估计表明西班牙裔男性中低骨密度和维生素D缺乏的负担相当大。
我们的研究结果强调了检查西班牙裔亚组骨骼健康的重要性，并表明相当数量的西班牙裔男性可能骨折和维生素D缺乏风险升高。
