一个可搜索的精神疾病遗传证据数据库。
A searchable database of genetic evidence for psychiatric disorders.
作者信息
Konneker Thomas, Barnes Todd, Furberg Helena, Losh Molly, Bulik Cynthia M, Sullivan Patrick F
机构信息
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7264, USA.
出版信息
Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B(6):671-5. doi: 10.1002/ajmg.b.30802.
Abstract
This paper describes a new bioinformatic tool for use in psychiatric research, "SLEP" (Sullivan Lab Evidence Project). SLEP is a searchable archive of findings from psychiatric genetics that is freely available on the web for non-commercial use (http://slep.unc.edu). Via a simple interface, users can retrieve findings from genome-wide linkage, genome-wide association, and microarray studies for ADHD, autism, bipolar disorder, eating disorders, major depression, nicotine dependence, and schizophrenia. Findings can be save to disk or viewed via a genome browser.
摘要
本文介绍了一种用于精神病学研究的新型生物信息学工具“SLEP”（沙利文实验室证据项目）。SLEP是一个可搜索的精神病遗传学研究结果档案库，可在网上免费供非商业使用（http://slep.unc.edu）。通过一个简单的界面，用户可以检索来自全基因组连锁、全基因组关联和微阵列研究的关于注意力缺陷多动障碍、自闭症、双相情感障碍、饮食失调、重度抑郁症、尼古丁依赖和精神分裂症的研究结果。研究结果可以保存到磁盘或通过基因组浏览器查看。
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