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持续非卧床腹膜透析(CAPD)中国患者淋巴吸收的影响因素

Factors affecting lymphatic absorption in Chinese patients on continuous ambulatory peritoneal dialysis (CAPD).

作者信息

Chan P C, Wu P G, Tam S C, Ip M S, Fang G X, Cheng I K

机构信息

Department of Medicine, University of Hong Kong, Queen Mary Hospital.

出版信息

Perit Dial Int. 1991;11(2):147-51.

PMID:1854872
Abstract

The pathways and physiology of lymph absorption (LA) from the peritoneal cavity are well documented; however, much uncertainty still exists as to the various clinical and demographic factors affecting LA. We studied LA measured by the albumin instillation method, in adult Chinese CAPD patients, and showed that it was independent of age, sex, body surface area, duration of dialysis, intrinsic renal disease, use of intraperitoneal drugs (heparin/antibiotics/deferroxamine) and frequency of past bacterial peritonitis. High lymph absorbers had a relatively higher transcapillary cumulative ultrafiltration than low lymph absorbers. An enhanced LA was associated with a high initial intraperitoneal volume. Assessment of diaphragmatic strength by the decrement in vital capacity on changing from an erect to a supine position failed to distinguish patients with high and low LA.

摘要

腹膜腔淋巴吸收(LA)的途径和生理学已有充分记录;然而,关于影响LA的各种临床和人口统计学因素仍存在很多不确定性。我们采用白蛋白注入法对成年中国持续性非卧床腹膜透析(CAPD)患者的LA进行了研究,结果显示LA与年龄、性别、体表面积、透析时间、内在肾病、腹膜内药物(肝素/抗生素/去铁胺)的使用以及既往细菌性腹膜炎的发作频率无关。高淋巴吸收者的跨毛细血管累积超滤量相对高于低淋巴吸收者。LA增强与初始腹膜内容量高有关。通过直立位改为仰卧位时肺活量的减少来评估膈肌力量,未能区分LA高和低的患者。

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