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[The convulsive activity of white rats after immunization with a conjugate of sidnofen and serum albumin].

作者信息

Danilova R A, Kustova E V, Obukhova M F, Ashmarin I P

出版信息

Biull Eksp Biol Med. 1991 Feb;111(2):137-9.

PMID:1854953
Abstract

The influence of white rats immunization by a covalent conjugate of serum albumin with sydnophen on the seizure activity in the single and repeated injections of pentylenetetrazole was investigated. The immunization lowered the seizure activity in single injections of threshold doses, (60 mg/kg) of pentylenetetrazole. The repeated daily injections of the drug in subthreshold doses (30 mg/kg) inhibited the process of "kindling" effects formation.

摘要

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