Steigstra H, Jansen R T, Baadenhuijsen H
Dutch Foundation for Quality Assessment in Clinical Chemistry, St. Radboud University Hospital, Nijmegen, The Netherlands.
Clin Chem. 1991 Jul;37(7):1196-204.
The Dutch Foundation for Quality Assessment in Clinical Chemistry (SKZL) is the professional organization that conducts external quality-assessment schemes in The Netherlands. However, such schemes in fact assess the performance of the internal quality-control systems of the participating laboratories. In this paper we describe a new concept, relating the data for internal control materials with those for external samples and thereby leading to a combined external/internal scheme (Combi). The statistical principles underlying the Combi scheme are discussed and examples of the graphical presentation of the results are shown. Because the laboratory data are transmitted over the public telephone system to the computers of the SKZL, we also describe the principles of the data communication. At two-month intervals a statistical presentation is sent to all participants. The central database is updated daily with the received results, making possible an on-line consultation regarding the statistics of the accumulated findings of the control materials in use.
荷兰临床化学质量评估基金会（SKZL）是在荷兰开展外部质量评估计划的专业组织。然而，此类计划实际上评估的是参与实验室内部质量控制系统的表现。在本文中，我们描述了一个新概念，即将内部控制材料的数据与外部样本的数据相关联，从而形成一个外部/内部联合计划（Combi）。讨论了Combi计划背后的统计原理，并展示了结果的图形表示示例。由于实验室数据通过公共电话系统传输到SKZL的计算机，我们还描述了数据通信的原理。每隔两个月会向所有参与者发送一份统计报告。中央数据库每天根据收到的结果进行更新，从而能够就正在使用的控制材料的累积结果的统计数据进行在线查询。
