Granger Nicolas, Stalin Catherine E, Brown Thomas B Harcourt, Jeffery Nick D
Department of Veterinary Medicine, The Queen's Veterinary School Hospital, University of Cambridge, Madingley Road, Cambridge CB3 0ES, United Kingdom.
J Feline Med Surg. 2008 Dec;10(6):603-7. doi: 10.1016/j.jfms.2008.03.008. Epub 2008 Jun 13.
This report describes a rapidly progressive loss of motor function in a 16-month-old male neutered Bengal cat, beginning in the pelvic limbs and progressing to involve all limbs and rendering the cat non-ambulatory. The neurological examination revealed flaccid tetraparesis with decreased spinal reflexes but preserved conscious proprioception and skin sensation. Extensive electrophysiological tests were conducted including electromyography, motor and sensory peripheral nerves potential recordings and 'late' potentials, defining the electrodiagnostic characteristics of this disease. Based on the electrophysiological findings, a generalised proximal and predominantly axonal neuropathy affecting the ventral (motor) nerve roots was suspected. As no aetiology was identified, this disease was classified as idiopathic polyradiculoneuropathy. Over a year, the cat presented three separate episodes of tetraparesis, each with a spontaneous complete recovery, consistent with the reportedly good prognosis for this disease.
本报告描述了一只16个月大已绝育的孟加拉猫运动功能迅速进行性丧失的情况,最初始于盆腔肢体,随后发展至累及所有肢体,导致该猫无法行走。神经系统检查显示弛缓性四肢轻瘫,脊髓反射减弱,但保留有意识本体感觉和皮肤感觉。进行了广泛的电生理测试,包括肌电图、运动和感觉外周神经电位记录以及“迟发”电位,以确定该疾病的电诊断特征。基于电生理检查结果,怀疑是一种影响腹侧(运动)神经根的广泛性近端且主要为轴索性多发神经病。由于未确定病因,该疾病被归类为特发性多神经根神经病。在一年多的时间里,这只猫出现了三次单独的四肢轻瘫发作,每次均自发完全恢复,这与据报道该疾病良好的预后相符。