Michail S, Preud'Homme D, Christian J, Nanagas V, Goodwin C, Hitch D, Mezoff A
Department of Pediatrics at Wright State University and The Children's Medical Center in Dayton, OH 45458, USA.
J Pediatr Surg. 2001 Sep;36(9):1394-6. doi: 10.1053/jpsu.2001.26379.
BACKGROUND/PURPOSE: Acalcular biliary pain is a term used to identify patients who have significant abdominal pain related to an abnormally low gallbladder ejection fraction in the absence of cholelithiasis. Little is known about this disease in the pediatric population. The aim of this study was to determine whether laparoscopic cholecystectomy is an effective method for treatment of children with abdominal pain in the setting of acalcular biliary pain and whether one can predict the outcome preoperatively.
The charts of all children who underwent laparoscopic cholecystectomy for acalcular biliary pain in our institution from January 1991 through April 1998 were reviewed. Sixty-three patients were identified as children with acalcular biliary pain who underwent laparoscopic cholecystectomy. Forty-eight patients were contacted successfully and they all completed the questionnaire. Complete resolution of abdominal pain occurred in 72%, and another 18% had near-complete resolution of pain. Some improvement was noted by 8%, and only 2% had no improvement. In a multiple logistic model, none of the variables were significant predictors of response outcome.
Laparoscopic cholecystectomy is an effective means of therapy for children with abdominal pain and low gallbladder ejection fraction. It is difficult to predict patients with complete response based on the preoperative clinical findings.
背景/目的:无结石性胆绞痛是一个用于识别那些在无胆石症情况下,因胆囊射血分数异常低而出现严重腹痛的患者的术语。在儿科人群中,对这种疾病了解甚少。本研究的目的是确定腹腔镜胆囊切除术是否是治疗无结石性胆绞痛患儿腹痛的有效方法,以及术前能否预测手术结果。
回顾了1991年1月至1998年4月在本机构因无结石性胆绞痛接受腹腔镜胆囊切除术的所有儿童的病历。确定63例无结石性胆绞痛患儿接受了腹腔镜胆囊切除术。成功联系到48例患者,他们均完成了问卷调查。72%的患者腹痛完全缓解,另有18%的患者疼痛接近完全缓解。8%的患者有一定改善,只有2%的患者无改善。在多元逻辑模型中,没有一个变量是反应结果的显著预测因素。
腹腔镜胆囊切除术是治疗腹痛且胆囊射血分数低的患儿的有效治疗手段。根据术前临床发现很难预测完全缓解的患者。