Montero Luis A, Hernanz de Lucas R, Hervás Morón A, Fernández Lizarbe E, Sancho García S, Vallejo Ocaña C, Polo Rubio A, Ramos Aguerri A
Department of Radiation Oncology, Hospital Ramón y Cajal, Madrid, Spain.
Clin Transl Oncol. 2008 Jun;10(6):334-46. doi: 10.1007/s12094-008-0209-6.
The concept of radiation therapy for the treatment of benign diseases refers to the use of moderate to high-energy ionising radiation as part of the treatment of non-malignant, but not necessarily harmless, diseases. The usefulness of radiation therapy, based on the anti-inflammatory properties of ionising radiation, has long been known. Apart from the treatment of intracranial benign tumours, such as meningiomas and neurinomas, the prevention of cardiovascular restenosis or treatment of skeletal degenerative diseases are, without doubt, the main fields of action for radiation therapy in benign conditions. Nonetheless, many other non-cancer entities may benefit from ionising radiation therapy treatment. The purpose of this review is to highlight and update indications for treatment with radiation therapy in benign conditions, focusing on skeletal degenerative processes, vascular conditions and soft tissue diseases.
用于治疗良性疾病的放射治疗概念是指使用中高能电离辐射作为治疗非恶性但不一定无害疾病的一部分。基于电离辐射的抗炎特性,放射治疗的有效性早已为人所知。除了治疗颅内良性肿瘤,如脑膜瘤和神经鞘瘤外,预防心血管再狭窄或治疗骨骼退行性疾病无疑是良性疾病放射治疗的主要作用领域。尽管如此,许多其他非癌症实体也可能从电离辐射治疗中受益。本综述的目的是突出并更新良性疾病放射治疗的适应证,重点关注骨骼退行性过程、血管疾病和软组织疾病。