Turhan Iyidir Ozlem, Cerit Ethem Turgay, Özkan Çiğdem, Altınova Eroğlu, Çimen Ali Rıza, Sözen Sinan, Kerem Mustafa, Aktürk Müjde, Memiş Leyla, Törüner Baloş, Çakır Nuri, Arslan Metin
Department of Endocrinology and Metabolism, Gazi University Faculty of Medicine, Ankara, Turkey.
Department of Urology, Gazi University Faculty of Medicine, Ankara, Turkey.
Case Rep Surg. 2016;2016:3768258. doi: 10.1155/2016/3768258. Epub 2016 Dec 20.
Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy. Sarcomatoid adrenal carcinoma is even more aggressive type of ACC. Bilateral malignant adrenal tumors are extremely rare except for those that represent metastasis from an extra-adrenal organ. Here we report a 53-year-old woman who presented with abdominal pain and weight loss. Abdominal computed tomography revealed bilateral adrenal masses and a mass in her liver. Surgical specimens showed pleomorphic tumor cells with epithelial and spindle cell morphology and immunohistochemical staining was compatible with sarcomatoid carcinoma. Sarcomatoid adrenal carcinoma should be kept in mind during the management of bilateral adrenal masses.
肾上腺皮质癌(ACC)是一种罕见的侵袭性恶性肿瘤。肉瘤样肾上腺皮质癌是ACC中侵袭性更强的一种类型。除了那些代表肾上腺外器官转移的肿瘤外,双侧恶性肾上腺肿瘤极为罕见。在此,我们报告一名53岁女性,她因腹痛和体重减轻前来就诊。腹部计算机断层扫描显示双侧肾上腺肿块以及肝脏内有一个肿块。手术标本显示具有上皮和梭形细胞形态的多形性肿瘤细胞,免疫组织化学染色结果与肉瘤样癌相符。在处理双侧肾上腺肿块时应考虑到肉瘤样肾上腺皮质癌。