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距肛缘5厘米内的恶性直肠梗阻:可扩张金属支架置入术有作用吗?

Malignant rectal obstruction within 5 cm of the anal verge: is there a role for expandable metallic stent placement?

作者信息

Song Ho-Young, Kim Jin Hyoung, Kim Kyung Rae, Shin Ji Hoon, Kim Hee Cheol, Yu Chang-Sik, Kim Jin Cheon

机构信息

Department of Radiology, Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Gastrointest Endosc. 2008 Oct;68(4):713-20. doi: 10.1016/j.gie.2007.12.051. Epub 2008 Jun 17.

Abstract

BACKGROUND

Placement of expandable metallic stents (EMS) has been considered contraindicated for patients with malignant rectal obstruction within 5 cm of the anal verge because of the potential problems of anal pain.

OBJECTIVE

Our purpose was to investigate the technical feasibility, clinical effectiveness, and safety of EMS placement in patients with malignant rectal obstruction within 5 cm of the anal verge.

DESIGN

Retrospective study.

SETTING

Single tertiary referral university hospital.

PATIENTS

The sites of obstruction included the rectum within 5 cm (range, 25-50 mm) of the anal verge in 16 patients (group A) and more than 5 cm (range, 53-74 mm) in 14 patients (group B).

INTERVENTIONS

Placement of 3 types of EMS.

MAIN OUTCOME MEASUREMENTS

Complications including pain were evaluated and compared between 2 groups with the Fisher exact test.

RESULTS

The overall technical success rate was 100%. Colon perforation occurred in 2 patients, who underwent emergency surgery. Ten (62.5%) of group A and 1 (7.1%) of group B complained of pain (P = .011). In 3 of the 10 patients in group A, the pain disappeared spontaneously within a week or was tolerated by the patients without use of analgesics, although the remaining 7 patients of group A and the 1 patient in group B needed analgesics until death or elective surgery.

LIMITATIONS

Retrospective study.

CONCLUSIONS

Placement of EMS in patients with malignant rectal obstruction within 5 cm of the anal verge seems feasible and relatively safe and may provide adequate palliation and preoperative decompression of obstruction symptoms. Anal pain was tolerable to the patients with or without use of analgesics.

摘要

背景

由于存在肛门疼痛的潜在问题,对于距肛缘5厘米以内的恶性直肠梗阻患者,放置可扩张金属支架(EMS)一直被视为禁忌。

目的

我们的目的是研究在距肛缘5厘米以内的恶性直肠梗阻患者中放置EMS的技术可行性、临床有效性和安全性。

设计

回顾性研究。

地点

单一的三级转诊大学医院。

患者

梗阻部位包括16例患者(A组)距肛缘5厘米以内(范围25 - 50毫米)的直肠和14例患者(B组)超过5厘米(范围53 - 74毫米)的直肠。

干预措施

放置3种类型的EMS。

主要观察指标

通过Fisher精确检验评估并比较两组包括疼痛在内的并发症。

结果

总体技术成功率为100%。2例患者发生结肠穿孔,接受了急诊手术。A组10例(62.5%)和B组1例(7.1%)主诉疼痛(P = 0.011)。A组10例患者中有3例疼痛在一周内自行消失或患者无需使用镇痛药即可耐受,尽管A组其余7例患者和B组1例患者直至死亡或择期手术都需要使用镇痛药。

局限性

回顾性研究。

结论

在距肛缘5厘米以内的恶性直肠梗阻患者中放置EMS似乎可行且相对安全,可能为梗阻症状提供充分的姑息治疗和术前减压。无论是否使用镇痛药,患者对肛门疼痛均可耐受。

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