Wuttikul Chatchada, Taoka Toshiaki, Akashi Toshiaki, Nakagawa Hiroyuki, Miyasaka Toshiteru, Sakamoto Masahiko, Takayama Katsutoshi, Wada Takeshi, Kitano Satoru, Takahama Junko, Marugami Nagaaki, Kichikawa Kimihiko
Department of Radiology, Nara Medical University, Kashihara, Nara, Japan.
Magn Reson Imaging. 2008 Dec;26(10):1374-80. doi: 10.1016/j.mri.2008.04.014. Epub 2008 Jun 18.
This study discusses prominent signal intensity of T(1)/T(2) prolongation of subcortical white matter within the anterior temporal region in premature infant brains that radiologists may encounter when interpreting conventional screening MRIs.
T(1)- and T(2)-weighted images of 69 preterm and term infants with no neurological abnormalities or developmental delays were evaluated retrospectively for areas of prominent signal intensity of T(1)/T(2) prolongation in white matter. We measured signal intensities of anterior temporal white matter, deep temporal white matter, frontopolar white matter and subcortical white matter of the precentral gyrus. We accessed chronological changes in signal intensity in the anterior and deep temporal white matter. We also analyzed variance tests among the signal intensity ratios to the ipsilateral thalamus of white matter areas by gestational age.
There was high frequency of prominent signal intensity of T(1)/T(2) prolongation in the temporal tip, particularly at a gestational age of 36-38 weeks. Signal intensity ratio of the anterior temporal white matter was lower on T(1)-weighted images and higher on T(2)-weighted images, and the finding became less prominent with increasing gestational age. The signal intensity ratios of anterior temporal white matter at a gestational age of 36-37 weeks and 38-39 weeks were significantly different from other regions.
Prominent signal intensity of T(1)/T(2) prolongation of subcortical white matter of the anterior temporal region is seen in normal premature infants, especially those at 36-39 gestational weeks. Although it is a prominent finding, radiologists should understand that these findings do not represent a pathological condition.
本研究探讨放射科医生在解读常规筛查磁共振成像（MRI）时，可能在早产儿脑内前颞区皮质下白质中遇到的T(1)/T(2)延长的显著信号强度。
回顾性评估69例无神经功能异常或发育迟缓的早产和足月婴儿的T(1)加权和T(2)加权图像，以观察白质中T(1)/T(2)延长的显著信号强度区域。我们测量了颞叶前部白质、颞叶深部白质、额极白质和中央前回皮质下白质的信号强度。我们观察了颞叶前部和深部白质信号强度的时间变化。我们还通过胎龄分析了白质区域与同侧丘脑信号强度比值之间的方差检验。
颞叶尖部T(1)/T(2)延长的显著信号强度出现频率较高，尤其是在孕36 - 38周时。颞叶前部白质在T(1)加权图像上信号强度比值较低，在T(2)加权图像上较高，且随着胎龄增加这一表现变得不那么明显。孕36 - 37周和38 - 39周时颞叶前部白质的信号强度比值与其他区域有显著差异。
在正常早产儿中，尤其是孕36 - 39周的早产儿，可见前颞区皮质下白质T(1)/T(2)延长的显著信号强度。尽管这是一个显著发现，但放射科医生应明白这些发现并不代表病理状况。
