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摩洛哥医护人员中的乙型肝炎

Hepatitis B in Moroccan health care workers.

作者信息

Djeriri K, Laurichesse H, Merle J L, Charof R, Abouyoub A, Fontana L, Benchemsi N, Elharti E, El Aouad R, Chamoux A, Beytout J

机构信息

Service Santé-Travail-Environnement, CHU Clermont-Ferrand, F-63003 Clermont-Ferrand, France.

出版信息

Occup Med (Lond). 2008 Sep;58(6):419-24. doi: 10.1093/occmed/kqn071. Epub 2008 Jun 18.

Abstract

AIM

To evaluate knowledge and perception of hepatitis B, including prevention, among Moroccan health care workers (HCWs) and to estimate seroprevalence of hepatitis B and vaccine coverage (VC).

METHODS

Four hundred and twenty HCWs were randomly selected and stratified by site: 120 in Rabat, 140 in Taza and 160 in Témara-Skhirat. The study included an anonymous questionnaire about knowledge of hepatitis B and its prevention and a serological survey. Oral statements and vaccine registers were used to analyse the VC of the HCWs. Serological testing and VC were analysed according to the occupational exposure.

RESULTS

Participation rates in the questionnaire and serological tests were 68% (285/420) and 66% (276/420), respectively. Fifteen (5%) HCWs had a history of hepatitis B. All HCWs considered that hepatitis B virus (HBV) infection may be acquired through blood exposure. Vaccination was acknowledged as a necessary means against HBV transmission by 276 (98%) HCWs. Forty-two per cent HCWs had no HBV serological markers. The prevalence of hepatitis B surface antigen was 1%. The mean prevalence of hepatitis B core antibody (anti-HBc) was 28% and was significantly higher (P < 0.05) among nursing auxiliaries (57%), nurses (30%), medical physicians (31%) and midwives (25%) than among laboratory technicians (13%). According to the vaccination registers (available in two sites), VC (> or =3 doses) was 55%. VC was 75% among midwives, 61% among nurses, 53% among nursing auxiliaries and 38% among medical staff. Of the fully vaccinated HCWs without anti-HBc, 51% had serological evidence of protection.

CONCLUSION

HBV vaccines should be more readily available for Moroccan HCWs by reinforcing current vaccination programmes.

摘要

目的

评估摩洛哥医护人员对乙型肝炎的了解和认知情况,包括预防方面,并估计乙型肝炎血清流行率和疫苗接种覆盖率(VC)。

方法

随机选取420名医护人员,并按工作地点分层:拉巴特120名、塔扎140名、特马拉 - 斯基拉特160名。该研究包括一份关于乙型肝炎及其预防知识的匿名问卷以及一项血清学调查。通过口头陈述和疫苗接种记录来分析医护人员的疫苗接种覆盖率。根据职业暴露情况分析血清学检测结果和疫苗接种覆盖率。

结果

问卷和血清学检测的参与率分别为68%(285/420)和66%(276/420)。15名(5%)医护人员有乙型肝炎病史。所有医护人员都认为乙型肝炎病毒(HBV)感染可通过血液暴露获得。276名(98%)医护人员认可接种疫苗是预防HBV传播的必要手段。42%的医护人员没有HBV血清学标志物。乙型肝炎表面抗原的流行率为1%。乙型肝炎核心抗体(抗 - HBc)的平均流行率为28%,在护理辅助人员(57%)、护士(30%)、医生(31%)和助产士(25%)中显著高于实验室技术人员(13%)(P < 0.05)。根据疫苗接种记录(两个地点可获取),疫苗接种覆盖率(≥3剂)为55%。助产士的疫苗接种覆盖率为75%,护士为61%,护理辅助人员为53%,医务人员为38%。在已全程接种疫苗且无抗 - HBc的医护人员中,51%有血清学保护证据。

结论

应加强当前的疫苗接种计划,使摩洛哥医护人员更容易获得HBV疫苗。

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