结构生物学：模拟胶原蛋白疾病。
Structural biology: Modelling collagen diseases.
作者信息
Brodsky Barbara, Baum Jean
出版信息
Nature. 2008 Jun 19;453(7198):998-9. doi: 10.1038/453998a.
Abstract
Mutations in collagen lead to hereditary disorders such as brittle-bone disease. Peptide models for aberrant collagens are beginning to clarify how these amino-acid replacements lead to clinical problems.
摘要
胶原蛋白的突变会导致诸如脆骨病等遗传性疾病。异常胶原蛋白的肽模型开始阐明这些氨基酸替代是如何导致临床问题的。
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