Harris Midori A
European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, Cambridge, UK.
Methods Mol Biol. 2008;452:111-24. doi: 10.1007/978-1-60327-159-2_5.
In recent years, biological ontologies have emerged as a means of representing and organizing biological concepts, enabling biologists, bioinformaticians, and others to derive meaning from large datasets.This chapter provides an overview of formal principles and practical considerations of ontology construction and application. Ontology development concepts are illustrated using examples drawn from the Gene Ontology (GO) and other OBO ontologies.
近年来,生物本体作为一种表示和组织生物学概念的手段应运而生,使生物学家、生物信息学家及其他人员能够从大型数据集中获取信息。本章概述了本体构建与应用的形式原则和实际考量。通过来自基因本体(GO)和其他开放生物学本体(OBO)本体的示例来说明本体开发概念。