The purpose of the study was to compare golf swing kinematics between female and male professional golfers, with particular focus on areas where different risks of injury exist and variables that may be related to driving distance. Twenty-five LPGA golfers and twenty-five PGA golfers were tested. Customized computer software was developed to analyze kinematic data obtained with an optoelectronic system at 240 Hz. At the peak of back swing, significant differences were found in trunk forward tilt (LPGA: 25 +/- 4 degrees and PGA: 31 +/- 4 degrees ), and in pelvis orientation (LPGA: 49 +/- 8 degrees and PGA: 42 +/- 7 degrees ). Significantly different pelvis rotation at the ball impact was found (LPGA: - 52 +/- 11 degrees and PGA: - 42 +/- 12 degrees ). The LPGA group produced significantly less angular velocities of the club shaft (2049 +/- 512 degrees /s), the left wrist (816 +/- 186 degrees /s), the right wrist (864 +/- 198 degrees /s) and the elbow extension (705 +/- 109 degrees /s) than the PGA group. The results of this study show there are differences in the swing mechanics for men and women at the professional level. Major differences were found at the wrist and elbow, where different incidences of injury were previously reported.