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[肝切除术治疗肝内胆管结石。单中心系列的近期和长期结果]

[Liver resection in the treatment of intrahepatic lithiasis. Immediate and long-term results in a single-center series].

作者信息

Marín C, Robles R, Pastor P, Parrilla P

机构信息

Departamento de Cirugía, Unidad de Cirugía Hepática y Transplante Hepática, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia.

出版信息

Rev Esp Enferm Dig. 2008 Apr;100(4):225-9. doi: 10.4321/s1130-01082008000400006.

Abstract

OBJECTIVE

intrahepatic lithiasis (IHL) is an uncommon entity in our environment. When associated with Caroli s disease or stenosis of the biliary radicals it may be necessary to perform liver resection to provide definitive resolution. We present immediate and long term results in a Spanish series of patients with hepatic resection to treat hepatolithiasis.

PATIENTS

between January 1996 and December 2007 we performed a liver resection (LR) in 8 patients for IHL. The IHL was associated with Caroli s disease in 3 cases and with stenosis of segmentary radicals in the other 5 cases. It manifested itself as acute cholangitis in 5 cases, as biliary colic in two cases and recurrent pancreatitis in one case. The surgical technique was 1 right hepatectomy, 2 left hepatectomies and 5 segmentary resections.

RESULTS

there was no intra- or postoperative mortality. The morbidity rate was 25%. One patient (12%) with Caroli s disease which had malignised to cholangiocarcinoma died in the follow-up period. The remaining 7 patients have had no IHL recurrence after a mean follow-up of 62 +/- 2 months (range: 31-106).

CONCLUSIONS

in our experience liver resection, either lobar or segmentary, is the treatment for patients with IHL associated with stenosis and dilatation of the bile duct, as it provides complete resolution of the disease with low rates of morbidity and mortality.

摘要

目的

肝内胆管结石(IHL)在我们所处环境中是一种不常见的病症。当它与卡罗利病或胆管分支狭窄相关联时,可能有必要进行肝切除以实现彻底治愈。我们展示了一组西班牙患者接受肝切除治疗肝内胆管结石的近期和长期结果。

患者

在1996年1月至2007年12月期间,我们对8例肝内胆管结石患者进行了肝切除(LR)。其中3例肝内胆管结石与卡罗利病相关,另外5例与节段性胆管分支狭窄相关。表现为急性胆管炎的有5例,胆绞痛的有2例,复发性胰腺炎的有1例。手术方式为1例右肝切除术,2例左肝切除术和5例节段性切除术。

结果

术中及术后均无死亡病例。发病率为25%。1例合并卡罗利病且已恶变为胆管癌的患者在随访期死亡。其余7例患者在平均随访62±2个月(范围:31 - 106个月)后肝内胆管结石无复发。

结论

根据我们的经验,肝叶或节段性肝切除是治疗伴有胆管狭窄和扩张的肝内胆管结石患者的方法,因为它能使疾病得到彻底治愈,且发病率和死亡率较低。

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