Jiang Hui, Wu Hong, Xu Ying-long, Wang Jing-zhou, Zeng Yong
Department of Hepatobiliary Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
HPB Surg. 2010;2010:791625. doi: 10.1155/2010/791625. Epub 2010 Mar 15.
Determination of first line treatment with limited hepatectomy or Anatomical hepatectomy provides better clinical outcome.
Immediate and long-term outcomes of 106 patients who underwent partial hepatectomy for RH at our institution from January 2001 to February 2005 were analyzed retrospectively. Clinical end-points included time to recovery of hepatic function, residual stones, infection of the liver remnant, bile leakage, recurrent stones, morbidity, and mortality.
LH was performed in 59 patients and AH in 47 patients as first-line treatment. The time of hepatic function recovery was not statistically different between the two groups (P > .05). However, Patients in AH group suffered from less residual stones (P < .05), less infection of the raw surface of liver remnant (P < .05), and less bile leakage (P < .05), with a median follow-up of 40.3 +/- 0.8 months (range 3-48), and AH group suffered a less recurrent stone rate (P < .05). No difference in morbidity, and mortality rates between the two groups.
AH is a safe and effective treatment for RH, with a fair rate of surgical complications, it should be considered as first-line treatment of RH.
确定有限肝切除术或解剖性肝切除术作为一线治疗是否能提供更好的临床结果。
回顾性分析2001年1月至2005年2月在我院接受肝内胆管结石(RH)部分肝切除术的106例患者的近期和长期结果。临床终点包括肝功能恢复时间、残余结石、肝残余感染、胆漏、复发性结石、发病率和死亡率。
59例患者接受有限肝切除术(LH)作为一线治疗,47例患者接受解剖性肝切除术(AH)作为一线治疗。两组肝功能恢复时间无统计学差异(P>.05)。然而,AH组患者残余结石较少(P<.05),肝残余创面感染较少(P<.05),胆漏较少(P<.05),中位随访时间为40.3±0.8个月(范围3 - 48个月),AH组复发性结石率较低(P<.05)。两组发病率和死亡率无差异。
AH是治疗肝内胆管结石的一种安全有效的方法,手术并发症发生率适中,应被视为肝内胆管结石的一线治疗方法。