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钝性创伤继发尿道狭窄患者勃起功能障碍的危险因素。

Risk factors for erectile dysfunction in patients with urethral strictures secondary to blunt trauma.

作者信息

Feng Chao, Xu Yue-Min, Yu Jian-Jun, Fei Xiao-Fang, Chen Lei

机构信息

Department of Urology, Sixth People's Hospital, Jiaotong University of Shanghai, Shanghai, People's Republic of China.

出版信息

J Sex Med. 2008 Nov;5(11):2656-61. doi: 10.1111/j.1743-6109.2008.00874.x. Epub 2008 Jun 17.

Abstract

INTRODUCTION

Erectile dysfunction (ED) is a well-known consequence of pelvic fracture, particularly in cases involving urethral injury. There are several risk factors that may be related to ED. However, no systemic approach is used to assess erectile function secondary to urethral trauma.

AIM

To investigate ED associated with urethral injury secondary to pelvic fracture and perineal trauma.

METHODS

Forty patients with traumatic urethral strictures secondary to blunt traumatic impact episode to the pelvis or perineum were included in our study. Pelvic fractures and urethral strictures were categorized according to injury types and radiological findings. All patients underwent nocturnal penile tumescence (NPT) monitoring, dynamic color-duplex Doppler ultrasonography (D-CDDU) before surgery. NPT monitoring was conducted again after surgery.

MAIN OUTCOME MEASURES

The events of NPT and D-CDDU were recorded.

RESULTS

In all patients, 11 had organic ED demonstrated by NPT. Vascular pathology was identified in three of 11 patients (27%). The peak systolic velocity of cavernosal artery was lower in patients with pubic diastasis in comparison to those without diastasis (P < 0.05). Significant changes in penile length and circumference were noted in posterior urethral injury compared with anterior urethral injury during erection (P < 0.05). The erectile duration time has a similar statistical difference in two groups mentioned above. However, no significant difference could be observed in the end-to-end anatomosis procedure before and after surgery (P > 0.05).

CONCLUSIONS

The pelvic fracture type, especially pubic diastasis, is a risk factor for ED following urethral injury. Location of the stricture is also a risk factor for subsequent erectile dysfunction.

摘要

引言

勃起功能障碍(ED)是骨盆骨折的一个众所周知的后果,尤其是在涉及尿道损伤的病例中。有几个风险因素可能与ED有关。然而,目前尚无用于评估尿道创伤继发勃起功能的系统方法。

目的

研究骨盆骨折和会阴创伤继发尿道损伤相关的ED。

方法

我们的研究纳入了40例因骨盆或会阴钝性创伤事件继发创伤性尿道狭窄的患者。根据损伤类型和影像学检查结果对骨盆骨折和尿道狭窄进行分类。所有患者在手术前行夜间阴茎勃起(NPT)监测、动态双功能彩色多普勒超声检查(D-CDDU)。术后再次进行NPT监测。

主要观察指标

记录NPT和D-CDDU事件。

结果

所有患者中,11例经NPT证实存在器质性ED。11例患者中有3例(27%)发现血管病变。耻骨联合分离患者海绵体动脉收缩期峰值流速低于无耻骨联合分离患者(P<0.05)。勃起时,后尿道损伤患者阴茎长度和周长的变化较前尿道损伤患者更为显著(P<0.05)。上述两组患者勃起持续时间也存在类似的统计学差异。然而,手术前后端端吻合手术无显著差异(P>0.05)。

结论

骨盆骨折类型,尤其是耻骨联合分离,是尿道损伤后发生ED的一个风险因素。狭窄部位也是随后发生勃起功能障碍的一个风险因素。

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