Popovich Kyle J, Hota Bala
Rush University Medical Center, Stroger Cook County Hospital, Chicago, Illinois, USA.
Dermatol Ther. 2008 May-Jun;21(3):167-79. doi: 10.1111/j.1529-8019.2008.00188.x.
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as a pathogen in the community with a range of clinical manifestations. Although skin and soft tissue infections (SSTIs) are the most common presentation, invasive and more virulent disease has been observed. Colonization and infection with CA-MRSA can occur in individuals with no prior healthcare exposures but also in distinct groups whose common characteristic appears to be close person-to-person contact. Outbreaks with CA-MRSA have occurred in day care centers, athletic teams, and prisons, and transmission has been documented among family members and within the hospital. Treatment of SSTIs involves incision and drainage, oral or parenteral antibiotic therapy, or topical therapy. Healthcare practitioners in outpatient and inpatient settings need to be familiar with prevention and treatment strategies for CA-MRSA.
社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）已成为社区中的一种病原体，具有一系列临床表现。虽然皮肤和软组织感染（SSTIs）是最常见的表现形式，但也观察到侵袭性更强、毒性更大的疾病。CA-MRSA的定植和感染可发生在既往无医疗接触史的个体中，也可发生在一些特定群体中，这些群体的共同特征似乎是密切的人际接触。CA-MRSA已在日托中心、运动队和监狱中爆发，并且已记录在家庭成员之间以及医院内的传播情况。SSTIs的治疗包括切开引流、口服或胃肠外抗生素治疗，或局部治疗。门诊和住院环境中的医疗从业者需要熟悉CA-MRSA的预防和治疗策略。
