Hanna Sammy A, Qureshi Yassar A, Bayliss Lee, David Lee A, O'Donnell Paul, Judson Ian R, Briggs Timothy W R
London Bone and Soft Tissue Tumour Service, Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, UK.
World J Surg Oncol. 2008 Jun 18;6:62. doi: 10.1186/1477-7819-6-62.
Myxoid liposarcoma is the second most commonly occurring sub-type of liposarcomas. In contrast to other soft tissue sarcomas, it is known to have a tendency to spread toward extrapulmonary sites, such as soft tissues, retroperitoneum, and the peritoneal surface. Bony spread, however, is not as common.
We report an unusual case of diffuse skeletal metastases from myxoid liposarcoma occurring 13 years after treatment of the primary tumour in the left lower limb. The skeletal spread of the disease was demonstrated on MRI only after other imaging modalities (plain radiography, CT and TC99 bone scans) had failed to detect these metastases.
MRI is an extremely sensitive and specific screening tool in the detection of skeletal involvement in these types of sarcomas, and therefore, should be a part of the staging process.
黏液样脂肪肉瘤是脂肪肉瘤中第二常见的亚型。与其他软组织肉瘤不同，已知其有向肺外部位扩散的倾向，如软组织、腹膜后和腹膜表面。然而，骨转移并不常见。
我们报告一例罕见病例，黏液样脂肪肉瘤在左下肢原发性肿瘤治疗13年后发生弥漫性骨骼转移。在其他影像学检查（平片、CT和TC99骨扫描）未能检测到这些转移灶后，MRI才显示出该疾病的骨骼扩散情况。
MRI是检测这类肉瘤骨骼受累的极其敏感和特异的筛查工具，因此，应成为分期过程的一部分。
