Ola S O, Otegbayo J A, Yakubu A, Odaibo G N, Olaleye D O
University of Ibadan, Department of Medicine, University College Hospital, Ibadan, Nigeria.
Trop Gastroenterol. 2008 Jan-Mar;29(1):32-4.
Various target groups have been identified in Nigeria for studying the prevalence of hepatitis B virus infection; however there is no information on its prevalence among workers in slaughter houses. This study determined the seroprevalence of hepatitis B virus infection in Nigerian butchers at Ibadan, and comprised 360 healthy Nigerian adult subjects (180 butchers, 180 traders as controls) selected by multistage stratified sampling. A questionnaire was used to collect relevant information and included points about risk behaviour. ELISA was used to detect the hepatitis B surface antigen in the serum; the seroprevalence rate in butchers and controls was 9.4% and 3.3%, respectively (p<0.05). Risk behaviour was seen more commonly in butchers than in controls. The presence of hepatitis B surface antigen in the serum was not related to the duration of occupational exposure or the number of partners. In summary, butchers comprise a high-risk occupational group for exposure to hepatitis B virus infection. We conclude that routine screening for parenterally acquired infections in this group is thus necessary in order to identify those who will require treatment and immunisation, especially against hepatitis B virus infection.
在尼日利亚，已确定了各类目标群体用于研究乙型肝炎病毒感染的流行情况；然而，关于屠宰场工人中该病毒的流行情况尚无相关信息。本研究测定了伊巴丹地区尼日利亚屠夫中乙型肝炎病毒感染的血清流行率，研究对象包括通过多阶段分层抽样选取的360名健康的尼日利亚成年受试者（180名屠夫，180名商人作为对照）。通过问卷调查收集相关信息，问卷内容包括风险行为相关要点。采用酶联免疫吸附测定法（ELISA）检测血清中的乙型肝炎表面抗原；屠夫组和对照组的血清流行率分别为9.4%和3.3%（p<0.05）。屠夫中出现风险行为的情况比对照组更为常见。血清中乙型肝炎表面抗原的存在与职业暴露时长或性伴侣数量无关。总之，屠夫是接触乙型肝炎病毒感染的高风险职业群体。我们得出结论，因此有必要对该群体进行经肠道外感染的常规筛查，以便识别出那些需要治疗和免疫的人，尤其是针对乙型肝炎病毒感染的免疫。
