Henriquez A H, Mendoza J, Gonzalez P C
Department of Medicine, San Juan de Dios Hospital, Santiago, Chile.
J Infect Dis. 1991 Aug;164(2):414-7. doi: 10.1093/infdis/164.2.414.
The study of anaerobic infections of the lung is usually limited to the use of invasive techniques such as transtracheal aspiration (TTA) to avoid contamination by oral flora. Bronchoalveolar lavage (BAL) has been used successfully in the study of the etiology of pneumonia in immunocompromised patients. This study evaluated the role of the quantitative culture of BAL in the diagnosis of lung abscess. Four episodes of lung abscess in three patients were studied, and the results of quantitative culture of BAL were compared with those of the standard technique of TTA. Nineteen anaerobic bacterial species were recovered from the BAL fluid, all but one at concentrations greater than 10(3) cfu/ml. Culture of BAL fluid yielded 18 of 22 of the isolates cultured from TTA, including 12 of 16 of the anaerobic bacteria. This study suggests that quantitative culture of BAL fluid may be useful in the bronchoscopic evaluation of lung abscess.
对肺部厌氧菌感染的研究通常局限于采用侵入性技术，如经气管抽吸术（TTA），以避免口腔菌群的污染。支气管肺泡灌洗术（BAL）已成功用于免疫功能低下患者肺炎病因的研究。本研究评估了BAL定量培养在肺脓肿诊断中的作用。研究了3例患者的4次肺脓肿发作，并将BAL定量培养结果与TTA标准技术的结果进行了比较。从BAL液中分离出19种厌氧菌，除1种外，所有菌种的浓度均大于10³cfu/ml。BAL液培养从TTA培养的22株分离菌中获得了18株，包括16株厌氧菌中的12株。本研究表明，BAL液定量培养可能有助于肺脓肿的支气管镜评估。
