Klionsky Daniel J
University of Michigan, Life Sciences Institute, Department of Molecular, Cellular and Developmental Biology, Ann Arbor, Michigan 48109-2216, USA.
Autophagy. 2008 Aug;4(6):740-3. doi: 10.4161/auto.6398. Epub 2008 Jun 9.
The word "autophagy" was invented by Christian de Duve, the discoverer of lysosomes, who also initiated the first experiments that provided clear biochemical proof of the involvement of lysosomes in this process. I recently had an opportunity to speak with de Duve and some of his former coworkers about their reminiscences of these events, and am pleased to share what they had to say with the readers of this journal, many of whom may not be familiar with this historical background to their field of interest.
“自噬”一词由溶酶体的发现者克里斯蒂安·德·迪夫创造,他还发起了首批实验,为溶酶体参与这一过程提供了明确的生化证据。最近我有机会与德·迪夫以及他的一些前同事交谈,了解他们对这些事件的回忆,并很高兴与本刊读者分享他们的讲述,因为本刊许多读者可能并不熟悉他们感兴趣领域的这一历史背景。