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Immunocytochemistry of neuron specific enolase (NSE) in the rat brain after single and repeated epileptic seizures.

作者信息

Yardimoğlu Melda, Ilbay Gul, Dalcik Cannur, Dalcik Hakki, Sahin Deniz, Ates Nurbay

机构信息

Department of Histology & Embryology, Kocaeli University, School of Medicine, Kocaeli, Turkey.

出版信息

Int J Neurosci. 2008 Jul;118(7):981-93. doi: 10.1080/00207450701769232.

DOI:10.1080/00207450701769232
PMID:18569155
Abstract

The aim of this study was to investigate neuron-specific enolase (NSE) immunoreactivity of the different brain regions after pentylenetetrazol (PTZ)- induced epileptic seizures in rats. Light microscopic examinations provided evidences for changes of neuronal activity after single and repeated seizures. The number of NSE (+) cells was well correlated with Nissl staining. The results suggest that NSE immunoreactivity may be a valuable marker for determination of the number of metabolically active neurons in different brain regions after single and repeated experimental seizures.

摘要

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