Motolese Pasquale
Center of Cosmetology, University of Ferrara, Ferrara, Italy.
J Cosmet Laser Ther. 2008 Jun;10(2):114-8. doi: 10.1080/14764170802074680.
This article re-examines and refutes the theories of intra-adipocyte lipolysis activated by phosphatidylcholine and by phospholipids in general, when injected into adipose tissue to reduce localized adiposity. These theories have not been confirmed and at times they conflict with current, although incomplete, knowledge relative to adipocyte metabolism. In particular, those regarding adipose tissues with little-known biochemical characteristics such as the primary localized adiposities. The use of the term 'lipolysis' is considered inappropriate; instead, these types of treatments should be indicated by the term 'adipocytolysis', given the demonstrated lytic activity of sodium deoxycholate on cell membranes, whose action, if not unique, is certainly prominent.
当将磷脂酰胆碱及一般的磷脂注射到脂肪组织以减少局部肥胖时，它们可激活脂肪细胞内的脂肪分解。这些理论尚未得到证实，并且有时与当前关于脂肪细胞代谢的知识（尽管并不完整）相冲突。特别是对于那些具有鲜为人知的生化特征的脂肪组织，如原发性局部肥胖。“脂肪分解”一词的使用被认为是不恰当的；相反，鉴于已证实脱氧胆酸钠对细胞膜具有溶解活性，其作用即便不是独一无二的，也肯定是显著的，因此这类治疗应使用“脂肪细胞溶解”这一术语来表示。
