Singh M, Porter C, Griffiths S
Victoria Health Centre, Nottingham, UK.
J Obstet Gynaecol. 2008 Apr;28(3):315-6. doi: 10.1080/01443610802044676.
This is a retrospective study of 614 women undergoing first trimester medical termination of pregnancy (TOP) from 1 January to 31 December 2006, at Nottingham Contraception and Sexual Health service. All women were in the gestational age of 6-9 weeks. The results showed that three women had blood loss of more than 500 ml and had to be transfused. All patients requiring blood transfusion were over 8 weeks' gestation. A total of 84 (13.8%) patients returned as planned to the unit for follow-up scan because of uncertainty over completeness of abortion. All patients (1.13%) who needed surgical intervention were more than 8 weeks' gestation. A total of 27 patients (4.3%) required admission overnight, the main indication being lack of support at home. Early medical TOP was successful in over 98% of women and allowed them to avoid the risks of surgical instrumentation and anaesthesia. Early medical abortion is a safe and effective procedure and deserves to be more widely available and utilised.
这是一项回顾性研究，研究对象为2006年1月1日至12月31日期间在诺丁汉避孕与性健康服务中心接受孕早期药物流产的614名女性。所有女性的孕周均在6至9周。结果显示，有三名女性失血超过500毫升，不得不接受输血。所有需要输血的患者孕周均超过8周。共有84名（13.8%）患者因对流产是否完全存在疑虑，按计划返回该科室进行随访扫描。所有需要手术干预的患者（1.13%）孕周均超过8周。共有27名患者（4.3%）需要过夜住院，主要原因是家中无人照料。早期药物流产在超过98%的女性中取得成功，使她们避免了手术器械操作和麻醉的风险。早期药物流产是一种安全有效的方法，值得更广泛地推广和应用。
