Akdal Gülden, Yener Görsev G, Kurt Pinar
Department of Neurology, School of Medicine, Dokuz Eylul University Inciralti, Izmir, Turkey.
Neurocase. 2008;14(2):147-50. doi: 10.1080/13554790802032242.
Vitamin B12 deficiency can manifest with various neuropsychiatric symptoms. We report a case of an individual with vitamin B12 deficiency presenting with personality, emotional and behavioral changes. Neuropsychological tests revealed disproportionate disturbance of executive functions. Single photon emission tomography (Tc99m HMPAO) showed right fronto-temporo-parietal hypoperfusion. After vitamin B12 injections, the patient's executive and behavioral dysfunction disappeared and performance on neuropsychological tests was once again in the normal range.
维生素B12缺乏可表现为多种神经精神症状。我们报告一例维生素B12缺乏患者，出现了人格、情绪和行为改变。神经心理学测试显示执行功能存在不成比例的障碍。单光子发射断层扫描（Tc99m HMPAO）显示右侧额颞顶叶灌注不足。维生素B12注射后，患者的执行和行为功能障碍消失，神经心理学测试表现再次恢复正常范围。
