伴有高血清血管紧张素转换酶的异常难治性创伤后葡萄膜炎——隐匿性眼部结节病？
Unusually resistant post-traumatic uveitis with high serum ACE--an occult ocular sarcoidosis?
作者信息
Petrou Petros, Reddy M Ashwin
机构信息
Barts and the Royal London Hospitals, London, United Kingdom.
出版信息
Ocul Immunol Inflamm. 2008 May-Jun;16(3):117-8. doi: 10.1080/09273940802051118.
PURPOSE
The initiation of acute anterior uveitis following non-penetrating trauma comprises a defined clinical entity although its pathophysiology is not yet completely understood.
DESIGN AND METHODS
Case presentation.
RESULTS
We present two cases of young boys in whom a first episode of resistant anterior uveitis developed following relatively minor non penetrating ocular injury. Further investigation revealed high levels of serum ACE in both cases.
CONCLUSION
To the best of our knowledge there are no previous published reports implicating minor ocular trauma in precipitating a first episode of uveitis associated with high serum ACE. A better understanding of the pathophysiology may provide insight into alternative treatments.
目的
尽管非穿透性眼外伤后急性前葡萄膜炎的病理生理学尚未完全明了，但它构成了一种明确的临床病症。
设计与方法
病例报告。
结果
我们报告两例年轻男孩，他们在相对轻微的非穿透性眼外伤后首次发生顽固性前葡萄膜炎。进一步检查发现两例患者血清ACE水平均升高。
结论
据我们所知，此前尚无关于轻微眼外伤引发与高血清ACE相关的首次葡萄膜炎发作的报道。对病理生理学的更好理解可能有助于探索替代治疗方法。
Zotero 插件