Hau J, Andersen L L, Poulsen O M, Krog N L, Worm K
Department of Pharmacology, Royal Veterinary and Agricultural University, Copenhagen, Denmark.
Lab Anim. 1991 Apr;25(2):122-5. doi: 10.1258/002367791781082522.
A cyclic variation in plasma levels of pregnancy-associated murine protein-1 (PAMP-1) during the oestrus cycle in outbred Pan: Thei mice was recorded. PAMP-1 plasma levels were significantly elevated in dioestrus as compared with the three other stages of the murine oestrus cycle. Until day 7 of gestation the PAMP-1 plasma levels remained low, and no significant differences could be observed between pregnant and pseudopregnant female mice. The PAMP-1 levels increased markedly in the circulation on day 8 of pregnancy, and continued to increase until peak values were reached at day 11 of pregnancy. In the latter half of pregnancy the PAMP-1 levels declined until day 17 of pregnancy, at which stage the normal non-pregnant values were recorded.
记录了远交系潘氏小鼠发情周期中妊娠相关小鼠蛋白-1（PAMP-1）血浆水平的周期性变化。与小鼠发情周期的其他三个阶段相比，PAMP-1血浆水平在间情期显著升高。直到妊娠第7天，PAMP-1血浆水平仍保持较低，妊娠和假孕雌性小鼠之间未观察到显著差异。在妊娠第8天，PAMP-1水平在循环中显著升高，并持续升高，直到妊娠第11天达到峰值。在妊娠后半期，PAMP-1水平下降，直到妊娠第17天，此时记录到正常非妊娠值。
