Carroll James D
Chirality. 2009 Mar;21(3):354-8. doi: 10.1002/chir.20590.
Chirality is often glossed over in theoretical or experimental discussions concerning the origin of life, but the ubiquity of homochiral building blocks in known biological systems demands explanation. Information theory can provide a quantitative framework for understanding the role of chirality in biology. Here I show how conclusions derived from information theory, in particular the concept of equivocation, can explain not only why chiral building blocks are necessary in living systems but also why a homochiral set of building blocks is necessary. These results lead to a new definition of life, and to the conclusion that the simplest form of life exists in the form of self-amplifying, autocatalytic reactions such as the Soai reaction.
在有关生命起源的理论或实验讨论中,手性常常被忽视,但已知生物系统中同手性构件的普遍存在需要作出解释。信息论可为理解手性在生物学中的作用提供一个定量框架。在此我展示了从信息论得出的结论,特别是含糊度的概念,不仅可以解释为什么手性构件在生命系统中是必要的,还能解释为什么需要一组同手性的构件。这些结果引出了生命的新定义,并得出结论:最简单的生命形式以自我放大的自催化反应(如索艾反应)的形式存在。