Haynes Robin, Pearce Jamie, Barnett Ross
School of Environmental Sciences, University of East Anglia, Norwich NR4 7TJ, United Kingdom.
Soc Sci Med. 2008 Sep;67(6):928-37. doi: 10.1016/j.socscimed.2008.05.005. Epub 2008 Jun 21.
This study investigated the combined effects of ethnicity, deprivation and geographical access to health services on the likelihood of survival from a range of common cancers in New Zealand. Individual cancer registry records of 99,062 cases of melanoma, colorectal, lung, breast and prostate cancers diagnosed in the period 1994-2004 were supplemented with small area information on social deprivation and estimates of travel time to the nearest primary care and cancer centre. Logistic regression was used to identify the variables associated with advanced extent of the disease at diagnosis. Adverse influences on survival were investigated using Cox proportional hazards models. Controlling for age and gender, Māori and Pacific peoples' ethnicity was strongly associated with poorer survival, partly because ethnicity was also linked to the likelihood of advanced disease at diagnosis. Living in a deprived area was related to later stage presentation and poorer survival of people with melanoma, but there was no other evidence that living in a deprived area or in a remote location were associated with later stage presentation. Some disease-specific trends in survival were observed. Colorectal and lung cancers were more likely to be fatal for people living in deprived areas, survival from prostate cancer was poor for men living remote from primary care, and people with colorectal, breast and prostate cancers had adverse survival chances if they lived distant from a cancer centre.
本研究调查了种族、贫困程度以及获得医疗服务的地理便利性对新西兰一系列常见癌症患者生存可能性的综合影响。在1994年至2004年期间确诊的99062例黑色素瘤、结直肠癌、肺癌、乳腺癌和前列腺癌的个体癌症登记记录,补充了关于社会贫困程度的小区域信息以及到最近的初级保健机构和癌症中心的旅行时间估计。使用逻辑回归来确定与诊断时疾病晚期程度相关的变量。使用Cox比例风险模型研究对生存的不利影响。在控制年龄和性别后,毛利人和太平洋岛民的种族与较差的生存率密切相关,部分原因是种族也与诊断时晚期疾病的可能性相关。生活在贫困地区与黑色素瘤患者的疾病晚期表现和较差的生存率有关,但没有其他证据表明生活在贫困地区或偏远地区与疾病晚期表现有关。观察到了一些特定疾病的生存趋势。生活在贫困地区的人患结直肠癌和肺癌更有可能致命,居住在远离初级保健机构的男性前列腺癌生存率较低,而结直肠癌、乳腺癌和前列腺癌患者如果居住在远离癌症中心的地方,生存机会则较差。