[广西省轮状病毒腹泻疫情调查]
[A research on rotaviral diarrhea outbreak in Guangxi Province].
作者信息
Li Dan-di, Mo Zhao-jun, Zhou Kai-jiao, Xie Hua-ping, Li Hai, Cui Shu-xian, Zhang Qing, Jin Miao, Yu Jie-mei, Xu Zi-qian, Zhang Dong-liang, Yuan Xin-hui, Cheng Wei-xia, Wang Zhong-shan, Fang Zhao-yin, Duan Zhao-jun
机构信息
Bethune College, Jilin University, Jilin, China.
出版信息
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2008 Apr;22(2):104-6.
OBJECTIVE
To analyze epidemiological characters of an outbreak of rotavirus diarrhea in Daxing County, Guangxi Province.
METHODS
Rotavirus-positive specimens were identified by ELISA kit. G/P typing assays were confirmed with multiplex seminested RT-PCR. Full-length VP7 genes of 4 positive specimens were amplified and analyzed.
RESULTS
30 cases of Rotavirus-positive were identified from 64 specimens. The attack rate was 46.9%, and G/P typing was G1P[8]. A change of VP7 amino acid residue is at positions 68.
CONCLUSION
G1P[8] rotavirus is the etiologic agents of this diarrhea outbreak. In addition, adults were included in this outbreak.
目的
分析广西壮族自治区大兴县一起轮状病毒腹泻暴发疫情的流行病学特征。
方法
采用ELISA试剂盒鉴定轮状病毒阳性标本。通过多重半巢式RT-PCR进行G/P分型检测。对4份阳性标本的全长VP7基因进行扩增和分析。
结果
从64份标本中鉴定出30例轮状病毒阳性病例。罹患率为46.9%，G/P分型为G1P[8]。VP7氨基酸残基在第68位发生改变。
结论
G1P[8]轮状病毒是此次腹泻暴发疫情的病原体。此外，此次疫情中有成人发病。
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