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对于肾细胞癌行肾切除术时,同侧肾上腺切除术并非必需。

[Ipsilateral adrenalectomy is not obligatory in nephrectomy for renal cell carcinoma].

作者信息

Aliaev Iu G, Akhvlediani N D, Blokhin P S

出版信息

Urologiia. 2008 Mar-Apr(2):16-22.

Abstract

To analyse the necessity of obligatory ipsilateral adrenalectomy (IA) for renal cell carcinoma (RCC), we made a study of 329 RCC patients operated from 2002 to 2007. Nephrectomy was conducted in 208 (63.2%) patients, renal resection--in 121 (36.8%), adrenalectomy--in 19 (5.8%) patients. High-contrast multislice computed tomography (HCMCT) was performed in all the patients. Preoperative HCMCT detected adrenal lesions in 62 (18.84%) patients. Adrenal adenoma was suspected in 39 (11.8%) patients: ipsilateral in 19 (48.77%), contralateral in 11 (28.23%), bilateral in 9 (23%) patients. Adrenal hyperplasy was diagnosed in 11 (3.34%) patients. It was ipsilateral in 5 (45.4%), contralateral in 4 (36.4%), bilateral in 2 (18.2%) patients. The tumor invaded the ipsilateral adrenal in 4 (1.2%) patients. A RCC metastasis into the adrenal was suspected in 8 (2.4%) patients. A synchroneous affection was seen in 5 (1.5%) patients: ipsilateral in 4 (80%) and bilateral in 1 (20%) patients. RCC invaded the ipsilateral adrenal in 1.2% patients with RCC, its adrenal metastasis was detected in 1.5% RCC patients. In preservation of the adrenal in adenoma or hyperplasy 5-year follow-up registered no changes. Neither pathological processes were diagnosed for 5 years in preservation of unaffected adrenal. Thus, adrenalectomy is not obligatory in radical nephrectomy.

摘要

为分析肾细胞癌(RCC)患者行患侧肾上腺切除术(IA)的必要性,我们对2002年至2007年期间接受手术的329例RCC患者进行了研究。208例(63.2%)患者行肾切除术,121例(36.8%)患者行肾脏部分切除术,19例(5.8%)患者行肾上腺切除术。所有患者均接受了高分辨率多层螺旋计算机断层扫描(HCMCT)。术前HCMCT检查发现62例(18.84%)患者存在肾上腺病变。39例(11.8%)患者疑似肾上腺腺瘤:患侧19例(48.77%),对侧11例(28.23%),双侧9例(23%)。11例(3.34%)患者诊断为肾上腺增生。患侧5例(45.4%),对侧4例(36.4%),双侧2例(18.2%)。4例(1.2%)患者肿瘤侵犯患侧肾上腺。8例(2.4%)患者疑似RCC转移至肾上腺。5例(1.5%)患者存在同步病变:患侧4例(80%),双侧1例(20%)。1.2%的RCC患者肿瘤侵犯患侧肾上腺,1.5%的RCC患者检测到肾上腺转移。对于腺瘤或增生患者保留肾上腺的5年随访未发现变化。保留未受影响的肾上腺5年内未诊断出病理过程。因此,根治性肾切除术中肾上腺切除术并非必要。

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