Gardner M O, Goldenberg R L
Department of Obstetrics and Gynecology, University of New Mexico, Albuquerque 87131-5286, USA.
Curr Opin Obstet Gynecol. 1996 Apr;8(2):106-9.
Corticosteroids used to enhance fetal maturation are one of the best studied interventions in perinatal medicine. The treatment has been shown to reduce neonatal morbidity and mortality. The intervention is also highly cost-effective. In this article, we review the evidence supporting the benefits of corticosteroids, controversial issues concerning their use, and current practice recommendations. The review will highlight the research presented at the recent National Institutes of Health Consensus Conference concerning corticosteroids. This research led the National Institutes of Health to advocate clinical practice guidelines on the appropriate use of corticosteroids.
用于促进胎儿成熟的皮质类固醇是围产期医学中研究最充分的干预措施之一。该治疗已被证明可降低新生儿发病率和死亡率。这种干预措施还具有很高的成本效益。在本文中，我们回顾了支持皮质类固醇益处的证据、有关其使用的争议问题以及当前的实践建议。该综述将重点介绍最近美国国立卫生研究院关于皮质类固醇的共识会议上提出的研究。这项研究促使美国国立卫生研究院倡导关于皮质类固醇合理使用的临床实践指南。
