El-Shanawany T, Williams P E, Jolles S
Department of Biochemistry and Immunology, University Hospital of Wales, Cardiff, UK.
Clin Exp Immunol. 2008 Jul;153(1):1-9. doi: 10.1111/j.1365-2249.2008.03694.x.
Anaphylaxis is a severe, life-threatening, generalized or systemic hypersensitivity reaction. While there is agreement as to this definition of anaphylaxis, the clinical presentation is often variable and it is not uncommon for there to be debate after the event as to whether anaphylaxis had actually occurred. The management of anaphylaxis falls into two distinct phases: (1) emergency treatment and resuscitation of a patient with acute anaphylaxis and (2) the search for a cause for the event and the formulation of a plan to prevent and treat possible further episodes of anaphylaxis. Both aspects are important in preventing death from anaphylaxis and are covered in this review.
过敏反应是一种严重的、危及生命的全身性或系统性超敏反应。虽然对于过敏反应的这一定义已达成共识,但临床表现往往各不相同,事后就是否实际发生过敏反应存在争议的情况也并不少见。过敏反应的管理分为两个不同阶段:(1)对急性过敏反应患者进行紧急治疗和复苏,以及(2)寻找该事件的原因并制定预防和治疗可能再次发生的过敏反应的计划。这两个方面对于预防过敏反应导致的死亡都很重要,本综述将对此进行阐述。