Expert Opin Pharmacother. 2013 May;14(7):827-30. doi: 10.1517/14656566.2013.781583. Epub 2013 Mar 19.
Anaphylaxis is an acute, life-threatening allergic emergency. Numerous studies have highlighted shortcomings in the emergency management of anaphylaxis, which is of considerable concern as sub-optimal immediate management increases the risk of poor outcomes. Death typically results from compromise of the cardiovascular and/or respiratory system and so emergency treatment should aim to restore blood pressure and relieve respiratory obstruction. This article provides insights on the recognition of anaphylaxis, summarises key clinically relevant insights from epidemiological investigations, and provides a state-of-the-art synopsis on the evidence-based emergency management of anaphylaxis.
过敏反应是一种急性的、危及生命的过敏紧急情况。许多研究都强调了过敏反应的紧急管理存在缺陷，这是一个非常令人担忧的问题，因为不适当的即时管理会增加不良结局的风险。死亡通常是由于心血管和/或呼吸系统受损所致，因此紧急治疗应旨在恢复血压和缓解呼吸阻塞。本文提供了对过敏反应识别的深入了解，总结了来自流行病学调查的关键临床相关见解，并提供了过敏反应循证紧急管理的最新概述。
