对变形鞭毛虫格氏耐格里原虫中紫外线和X射线辐射造成的损伤进行修复。
Repair of damage caused by UV- and X-irradiation in the amoeboflagellate Naegleria gruberi.
作者信息
Hillebrandt S, Müller I
机构信息
Institut für Entwicklungsphysiologie der Universität zu Köln, Federal Republic of Germany.
出版信息
Radiat Environ Biophys. 1991;30(2):123-30. doi: 10.1007/BF01219346.
Cysts of Naegleria gruberi have a normal UV- and an extremely high X-ray resistance compared to other protozoans. Caffeine and 3-aminobenzamide applied to excysting amoeba after irradiation in the encysted state (UV and X-rays) by feeding with drug-containing bacteria increased lethality, while fractionated irradiation (UV) and liquid-holding (UV and X-rays) increased survival. Illumination with visible light after UV-irradiation restored almost 100% viability. The results are discussed in regard to the activity of repair mechanisms.
与其他原生动物相比，格氏耐格里变形虫的囊肿具有正常的紫外线抗性和极高的X射线抗性。在包囊状态下（紫外线和X射线）照射后，通过喂食含药细菌，将咖啡因和3-氨基苯甲酰胺应用于正在脱囊的变形虫会增加杀伤力，而分次照射（紫外线）和液体保存（紫外线和X射线）则会提高存活率。紫外线照射后用可见光照射可使存活率恢复近100%。结合修复机制的活性对结果进行了讨论。
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