Sakurai Nobuyuki, Tateoka Kazuhiro, Taguchi Jun, Terada Tadashi
Department of Obstetrics and Gynecology, Shizuoka Municipal Shimizu Hospital, Miyakami 1231, Shimizu-ku, Shizuoka 424-8636, Japan.
Int J Gynecol Pathol. 2008 Jul;27(3):412-7. doi: 10.1097/PGP.0b013e31815ea7e3.
Primary ovarian lymphoma is a rare disease, and its definition is still controversial. Many cases of primary ovarian lymphoma are diagnosed as diffuse large B-cell type, whereas the precursor lymphoblastic type is extremely rare. Herein, we describe a case of precursor B-cell lymphoblastic lymphoma of the ovary that was successfully treated with surgery and chemotherapy. A 19-year-old woman presented ovarian tumors and paraaortic lymphoadenopathy, which were suggestive of advanced ovarian cancer. Exploratory laparotomy and right salpingo-oophorectomy were performed, and the diagnosis of precursor B-cell lymphoblastic lymphoma was established. The patient was treated with a combination of chemotherapy and is currently disease-free 1 year after surgery. To our best knowledge, this is the fourth reported case of precursor lymphoblastic lymphoma of the ovary.
原发性卵巢淋巴瘤是一种罕见疾病，其定义仍存在争议。许多原发性卵巢淋巴瘤病例被诊断为弥漫性大B细胞型，而前驱淋巴细胞母细胞型极为罕见。在此，我们描述一例经手术和化疗成功治疗的卵巢前驱B细胞淋巴细胞母细胞淋巴瘤病例。一名19岁女性出现卵巢肿瘤和腹主动脉旁淋巴结肿大，提示晚期卵巢癌。进行了剖腹探查术和右侧输卵管卵巢切除术，并确诊为前驱B细胞淋巴细胞母细胞淋巴瘤。该患者接受了化疗联合治疗，目前术后1年无疾病复发。据我们所知，这是第四例报告的卵巢前驱淋巴细胞母细胞淋巴瘤病例。
